Disufenton natrijum : Osobine, Reference, Literatura, Spoljašnje veze Википедија

Disufenton natrijum

Disufenton natrijum
Klinički podaci

Drugs.com	sodium.html Monografija
Identifikatori
ATC kod	none
PubChem	CID 6440181
UNII	7M1J3HN9VO^Y
KEGG	D03875^Y
Hemijski podaci
Formula	C₁₁H₁₃NNa₂O₇S₂
Molarna masa	381,333
SMILES [Na+].[Na+].CC(C)(C)\[N+](=C\c1ccc(cc1S(=O)(=O)[O-])S(=O)(=O)[O-])\[O-]
InChI InChI=1S/C11H15NO7S2.2Na/c1-11(2,3)12(13)7-8-4-5-9(20(14,15)16)6-10(8)21(17,18)19;;/h4-7H,1-3H3,(H,14,15,16)(H,17,18,19);;/q;2*+1/p-2/b12-7-;;^Y Key:XLZOVRYBVCMCGL-BPNVQINPSA-L^Y

Disufenton natrijum je organsko jedinjenje, koje sadrži 11 atoma ugljenika i ima molekulsku masu od 381,333 Da.

Osobine

Osobina	Vrednost
Broj akceptora vodonika	7
Broj donora vodonika	0
Broj rotacionih veza	4
Particioni koeficijent^[1] (ALogP)	-4,0
Rastvorljivost^[2] (logS, log(mol/L))	-2,5
Polarna površina^[3] (PSA, Å²)	289,4

^ Ghose, A.K.; Viswanadhan V.N. & Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods”. J. Phys. Chem. A. 102: 3762—3772. doi:10.1021/jp980230o.
^ Tetko IV, Tanchuk VY, Kasheva TN, Villa AE (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”. Chem Inf. Comput. Sci. 41: 1488—1493. PMID 11749573. doi:10.1021/ci000392t.
^ Ertl P.; Rohde B.; Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties”. J. Med. Chem. 43: 3714—3717. PMID 11020286. doi:10.1021/jm000942e.

Hardman JG, Limbird LE, Gilman AG (2001). Goodman & Gilman's The Pharmacological Basis of Therapeutics (10. изд.). New York: McGraw-Hill. ISBN 0071354697. doi:10.1036/0071422803.
Thomas L. Lemke; David A. Williams, ур. (2007). Foye's Principles of Medicinal Chemistry (6. изд.). Baltimore: Lippincott Willams & Wilkins. ISBN 0781768799.